Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features
Identifieur interne : 000B33 ( Main/Exploration ); précédent : 000B32; suivant : 000B34Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features
Auteurs : Ya-Fang Wang [Taïwan] ; Chuan-Fa Chang [Taïwan] ; Chia-Yu Chi [Taïwan] ; Hsuan-Chen Wang [Taïwan] ; Jen-Ren Wang [Taïwan] ; Ih-Jen Su [Taïwan]Source :
- Journal of Medical Virology [ 0146-6615 ] ; 2012-04.
Abstract
The carbohydrate binding specificities are different among avian and human influenza A viruses and may affect the tissue tropism and transmission of these viruses. The glycan binding biology for influenza B, however, has not been systematically characterized. Glycan binding specificities of influenza B viral isolates were analyzed and correlated to hemagglutinin (HA) genotypes and clinical manifestations. A newly developed solution glycan array was applied to characterize the receptor binding specificities of influenza B virus clinical isolates from 2001 to 2007 in Taiwan. Thirty oligosaccharides which include α‐2,3 and α‐2,6 linkage glycans were subjected to analysis. The glycan binding patterns of 53 influenza B isolates could be categorized into three groups and were well correlated to their HA genotypes. The Yamagata‐like strains predominantly bound to α‐2,6‐linkage glycan (24:29, 83%) while Victoria‐like strains preferentially bound to both α‐2,3‐ and α‐2,6‐linkage glycans (13:24, 54%). A third group of viruses bound to sulfated glycans and these all belonged to Victoria‐like strains. Based on the HA sequences, Asn‐163, Glu‐198, Ala‐202, and Lys‐203 were conserved among Victoria‐like strains which may influence their carbohydrate recognition. The viruses bound to dual type glycans were more likely to be associated with the development of bronchopneumonia and gastrointestinal illness than those bound only to α‐2,6 sialyl glycans (P < 0.05). Glycan binding analyses provide additional information to monitor the antigenic shift, tissue tropism, and transmission capability of influenza B viruses, and will contribute to virus surveillance and vaccine strain selection. J. Med. Virol. 84:679–685, 2012. © 2011 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/jmv.23219
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001105
- to stream Istex, to step Curation: 001105
- to stream Istex, to step Checkpoint: 000110
- to stream Main, to step Merge: 000B36
- to stream Main, to step Curation: 000B33
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features</title><author><name sortKey="Wang, Ya Ang" sort="Wang, Ya Ang" uniqKey="Wang Y" first="Ya-Fang" last="Wang">Ya-Fang Wang</name></author><author><name sortKey="Chang, Chuan A" sort="Chang, Chuan A" uniqKey="Chang C" first="Chuan-Fa" last="Chang">Chuan-Fa Chang</name></author><author><name sortKey="Chi, Chia U" sort="Chi, Chia U" uniqKey="Chi C" first="Chia-Yu" last="Chi">Chia-Yu Chi</name></author><author><name sortKey="Wang, Hsuan Hen" sort="Wang, Hsuan Hen" uniqKey="Wang H" first="Hsuan-Chen" last="Wang">Hsuan-Chen Wang</name></author><author><name sortKey="Wang, Jen En" sort="Wang, Jen En" uniqKey="Wang J" first="Jen-Ren" last="Wang">Jen-Ren Wang</name></author><author><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:041341ED962DA34F6AC0E2F73342C1BFC7812270</idno><date when="2012" year="2012">2012</date><idno type="doi">10.1002/jmv.23219</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-4PWVX7JR-P/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">001105</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001105</idno><idno type="wicri:Area/Istex/Curation">001105</idno><idno type="wicri:Area/Istex/Checkpoint">000110</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000110</idno><idno type="wicri:doubleKey">0146-6615:2012:Wang Y:characterization:of:glycan</idno><idno type="wicri:Area/Main/Merge">000B36</idno><idno type="wicri:Area/Main/Curation">000B33</idno><idno type="wicri:Area/Main/Exploration">000B33</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features</title><author><name sortKey="Wang, Ya Ang" sort="Wang, Ya Ang" uniqKey="Wang Y" first="Ya-Fang" last="Wang">Ya-Fang Wang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Center of Infectious Disease and Signaling Research, Medical College, National Cheng Kung University, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation></author><author><name sortKey="Chang, Chuan A" sort="Chang, Chuan A" uniqKey="Chang C" first="Chuan-Fa" last="Chang">Chuan-Fa Chang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Center of Infectious Disease and Signaling Research, Medical College, National Cheng Kung University, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Departments of Medical Laboratory Science and Biotechnology, National Cheng Kung University Medical School and Hospital, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation></author><author><name sortKey="Chi, Chia U" sort="Chi, Chia U" uniqKey="Chi C" first="Chia-Yu" last="Chi">Chia-Yu Chi</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Departments of Pediatrics, National Cheng Kung University Medical School and Hospital, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Hsuan Hen" sort="Wang, Hsuan Hen" uniqKey="Wang H" first="Hsuan-Chen" last="Wang">Hsuan-Chen Wang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Jen En" sort="Wang, Jen En" uniqKey="Wang J" first="Jen-Ren" last="Wang">Jen-Ren Wang</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Center of Infectious Disease and Signaling Research, Medical College, National Cheng Kung University, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Departments of Medical Laboratory Science and Biotechnology, National Cheng Kung University Medical School and Hospital, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Departments of Pathology, National Cheng Kung University Medical School and Hospital, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation></author><author><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>National Institute of Infectious Disease and Vaccinology, National Health Research Institutes, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Center of Infectious Disease and Signaling Research, Medical College, National Cheng Kung University, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Taïwan</country><wicri:regionArea>Departments of Pathology, National Cheng Kung University Medical School and Hospital, Tainan</wicri:regionArea><wicri:noRegion>Tainan</wicri:noRegion></affiliation><affiliation wicri:level="1"><country wicri:rule="url">Taïwan</country></affiliation><affiliation wicri:level="1"><country xml:lang="fr" wicri:curation="lc">Taïwan</country><wicri:regionArea>Correspondence address: National Institues of Infectious Diseases and Vaccinology, National Health Research Institutes, No. 367 Sheng‐Li Road, Tainan 70456</wicri:regionArea><wicri:noRegion>Tainan 70456</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Journal of Medical Virology</title><title level="j" type="alt">JOURNAL OF MEDICAL VIROLOGY</title><idno type="ISSN">0146-6615</idno><idno type="eISSN">1096-9071</idno><imprint><biblScope unit="vol">84</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="679">679</biblScope><biblScope unit="page" to="685">685</biblScope><biblScope unit="page-count">7</biblScope><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2012-04">2012-04</date></imprint><idno type="ISSN">0146-6615</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0146-6615</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The carbohydrate binding specificities are different among avian and human influenza A viruses and may affect the tissue tropism and transmission of these viruses. The glycan binding biology for influenza B, however, has not been systematically characterized. Glycan binding specificities of influenza B viral isolates were analyzed and correlated to hemagglutinin (HA) genotypes and clinical manifestations. A newly developed solution glycan array was applied to characterize the receptor binding specificities of influenza B virus clinical isolates from 2001 to 2007 in Taiwan. Thirty oligosaccharides which include α‐2,3 and α‐2,6 linkage glycans were subjected to analysis. The glycan binding patterns of 53 influenza B isolates could be categorized into three groups and were well correlated to their HA genotypes. The Yamagata‐like strains predominantly bound to α‐2,6‐linkage glycan (24:29, 83%) while Victoria‐like strains preferentially bound to both α‐2,3‐ and α‐2,6‐linkage glycans (13:24, 54%). A third group of viruses bound to sulfated glycans and these all belonged to Victoria‐like strains. Based on the HA sequences, Asn‐163, Glu‐198, Ala‐202, and Lys‐203 were conserved among Victoria‐like strains which may influence their carbohydrate recognition. The viruses bound to dual type glycans were more likely to be associated with the development of bronchopneumonia and gastrointestinal illness than those bound only to α‐2,6 sialyl glycans (P < 0.05). Glycan binding analyses provide additional information to monitor the antigenic shift, tissue tropism, and transmission capability of influenza B viruses, and will contribute to virus surveillance and vaccine strain selection. J. Med. Virol. 84:679–685, 2012. © 2011 Wiley Periodicals, Inc.</div></front></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Wang, Ya Ang" sort="Wang, Ya Ang" uniqKey="Wang Y" first="Ya-Fang" last="Wang">Ya-Fang Wang</name></noRegion><name sortKey="Chang, Chuan A" sort="Chang, Chuan A" uniqKey="Chang C" first="Chuan-Fa" last="Chang">Chuan-Fa Chang</name><name sortKey="Chang, Chuan A" sort="Chang, Chuan A" uniqKey="Chang C" first="Chuan-Fa" last="Chang">Chuan-Fa Chang</name><name sortKey="Chi, Chia U" sort="Chi, Chia U" uniqKey="Chi C" first="Chia-Yu" last="Chi">Chia-Yu Chi</name><name sortKey="Chi, Chia U" sort="Chi, Chia U" uniqKey="Chi C" first="Chia-Yu" last="Chi">Chia-Yu Chi</name><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name><name sortKey="Su, Ih En" sort="Su, Ih En" uniqKey="Su I" first="Ih-Jen" last="Su">Ih-Jen Su</name><name sortKey="Wang, Hsuan Hen" sort="Wang, Hsuan Hen" uniqKey="Wang H" first="Hsuan-Chen" last="Wang">Hsuan-Chen Wang</name><name sortKey="Wang, Jen En" sort="Wang, Jen En" uniqKey="Wang J" first="Jen-Ren" last="Wang">Jen-Ren Wang</name><name sortKey="Wang, Jen En" sort="Wang, Jen En" uniqKey="Wang J" first="Jen-Ren" last="Wang">Jen-Ren Wang</name><name sortKey="Wang, Jen En" sort="Wang, Jen En" uniqKey="Wang J" first="Jen-Ren" last="Wang">Jen-Ren Wang</name><name sortKey="Wang, Jen En" sort="Wang, Jen En" uniqKey="Wang J" first="Jen-Ren" last="Wang">Jen-Ren Wang</name><name sortKey="Wang, Ya Ang" sort="Wang, Ya Ang" uniqKey="Wang Y" first="Ya-Fang" last="Wang">Ya-Fang Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/H2N2V1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B33 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000B33 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= H2N2V1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:041341ED962DA34F6AC0E2F73342C1BFC7812270
|texte= Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features
}}
| This area was generated with Dilib version V0.6.33. |  |